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Georgios I. Laliotis
European Journal of Case Reports
Editor Name: Georgios I. Laliotis
Country: Greece
University: University Of Crete
Designation: M.D
Department: Laboratory of Cancer
Biology
Email: glaliot7@gmail.com; georgios.laliotis@osumc.edu
BIOGRAPHY:
Education:
1. University Of Crete, School Of
Medicine ” 2011-2017, Medical Degree, (M.D.) GPA 8.59 summa cum ladae.
2. University Of Crete, School Of
Medicine -2018-Present. Doctor of Philosophy, (Ph.D.), ˜The epigenetic
regulation of U2AF2 pre-mRNA alternative splicing by AKT3-phosphorylated IWS1,
controls the genomic stability and the therapeutic response of PD-L1 blockade
in patients with Lung Adenocarcinoma™. Expected Graduation September 2021.
3. The Ohio State University, College
of Public Health- 2019-Expected Graduation May 2021, Master of Public Health
(M.P.H)-The Master of Public Health - Program for Experienced Professionals
(MPH-PEP), Clinical Translational Medicine
HONORS
AND AWARD
2011: State Scholarship Foundation -
Scholarship for the top 10 students entering University Of Crete, Medical
School
2013: State Scholarship Foundation -
Scholarship for 2nd best student in University Of Crete, School Of Medicine in
2nd medical year
2015: State Scholarship Foundation -
Scholarship for 2nd best student in University Of Crete, School Of Medicine in
4th medical year
2016: 2nd place -International Quiz Of
Medical Knowledge -10th Hellenic Congress Of Medical Students, Patra, May 2016
2017: Stavros Nirachos Foundation
Scholarship for Scientific Excellence- Scholarship for graduating 2nd from University
of Crete, School of Medicine.
2018: The Pelotonia Post-Doctoral
Scholarship for cancer Research- The Ohio State University Comprehensive Cancer
Center, Columbus, OH
RESEARCH
EXPERIENCE
1. Laboratory of Cancer Biology,
University Of Crete, 2011-2014 Pharmacogenomic project (gene expression
profiles, SNPs analysis, and mutations analysis)-Establishment of markers for
evaluation of micrometastatic disease in patients with colorectal cancer-Mentor
: Ass. Prof. Ioannis Sougklakos
2. Laboratory of Infectious Diseases,
University Of Crete, 2015-201 fungal infections and antimicrobial agents in
immunosuppressant patients - Mentor: Prof.George Samonis.
3. Official Member of Clinical Trial
Unit in Oncology Department “ University Hospital Of Heraklion,
2015-2017. Participating in organising and analysing the protocols and
results of double-blinded stage 2 and 3 clinical trials for anti-neoplasmatic
therapies in oncologic patients - Mentors: Ass. Prof. Ioannis Sougklakos -
Prof. George Samonis.
4. Member of HALT-3 trial team assigned
by Hellenic Centre of Disease Control: June 2016-December 2017. Protocol for
point prevalence surveys of healthcare-associated infections and antimicrobial
use in long-term care facilities in Crete - Mentor: Prof. Of Infectious
Diseases Achilleas Gkikas.
5. Post-Doctoral Research Fellow,
Molecular Oncology Research Institute, Tufts Medical Center, Boston, MA.
December 2017-April 2018.
6. Post-Doctoral Research Fellow, The
Ohio State Comprehensive Cancer Center- James and Solove Research Institute,
Columbus, OH. May 2018-Present.
PROFESSIONAL
EXPERIENCE
Clinical Elective- Boston Medical
Center, Department of Nephrology, March 2018-April 2018.
Supervisors : Rivka Avalon, M.D.
Associate Professor, Boston University School Of Medicine, Laurence H. Beck,
M.D., Ph.D., Associate Professor, Boston University School Of Medicine, Boston,
MA.
September 2015-January 2016 -
University Hospital Of Heraklion : Clinical Clerkship in Surgery - rotated in :
orthopedics, intensive care unit, urology , surgical oncology, general surgery.
February 2016-June 2016 - University
Hospital Of Heraklion : Clinical Clerkship in Internal Medicine - rotated in :
infectious diseases , geriatrics, nephrology, cardiology, pneumonology,
gastroenterology.
September 2016-January 2017 -
University Hospital Of Heraklion : Clinical Clerkship in Obstetrics, Emergency
Unit, pediatrics
February 2017-June 2017 - University
Hospital of Heraklion : Clinical Clerkship in Opthalmology, INT, Neurology,
Psychiatry, Primary Care.
PUBLICATIONS
1. Kountourakis, P., Souglakos, J.,
Gouvas, N., Androulakis, N., Laliotis G., Athanasiadis, A., Boukovinas, I., ...
& Georgiou, P. (2016). Adjuvant chemotherapy for colon cancer: a consensus
statement of the Hellenic and Cypriot Colorectal Cancer Study Group by the
HeSMO. Annals of gastroenterology: quarterly publication of the Hellenic
Society of Gastroenterology, 29(1), 18.
2. Laliotis G., Paraskevopoulou M,
Taraslia V., Vlahos I, Palmieri D., Coppola V., Carbonne D and Philip N.
Tsichlis., The epigenetic regulation of U2AF2 pre-mRNA alternative splicing by
AKT3-phosphorylated IWS1, controls the genomic stability and the therapeutic
response of DL1 blockade in patients with Lung Adenocarcinoma™,
manuscript under review in Cancer Cell™.Â
3. Laliotis G., Paraskevopoulou M,
Palmieri D., Chavdoula E., Coppola V., and Philip N. Tsichlis. IWS1 regulates
ROS formation and response to cisplatin treatment by regulating the xCT/SLC7A11
cysteine transporter transcription in lung adenocarcinoma™, manuscript
submitted and under review in Molecular Cell™.
4. Laliotis G., Peter Vogt and Philip
N. Tsichlis, Phosphoinositide 3-kinase, a Field in Transition™, invited Review
article submitted in Special Issue of MDPI Biomolecules™.
5. Anastas V., Laliotis G., Chavdoula
E. And Philip N. Tsichlis The crosstalk of H3K36me3 and H3K27me3 in human
cancer and disease™, Invited Review Article submitted in Cells™
PRESENTAΤIONS/POSTERS
1. Laliotis G., Paraskevopoulou M,
Taraslia V., Vlahos I, Palmieri D., Coppola V., Orlacchio A. and Philip
N. Tsichlis. IWS1/AKT3 axis controls the alternative splicing of U2AF2 and
regulates the DNA Damage response through regulation of p21/PUMA splicing.™,
American Association of Cancer Research 2019 Annual Meeting, March 29-April
2019, Atlanta, GA.
2. Laliotis G., Paraskevopoulou M,
Taraslia V., Vlahos I, Palmieri D., Coppola V., and Philip N. Tsichlis, p-IWS1/AKT3
axis control U2AF2 alternative pre-mRNA splicing by increased H3K36me3
distribution and recruitment of LEGDF-SRSF1 spliceosomal complex™, 84th Cold
Spring Harbor Laboratory Symposium, RNA Control and regulation™, May 29-June 3,
One Bungtown Road, Cold Spring Harbor, NY.
3. Review of Hereditary Breast cancer
syndromes™, 4th Alumni Meeting of Cretan Association of Surgical Oncology,
Heraklion, April, 2017.
4. Review of available and future
treatments in metastatic melanoma', 3rd Alumni Meeting of Cretan Association of
Surgical Oncology, Heraklion, May, 2016
5. Umbilical cord hematopoietic stem
cells : properties and clinical applications' , 10th Hellenic Congress Of
Medical Students, Patra, May 2016.
6. Potential Applications Of Circulated
Tumor Cells in clinical drug development for metastatic colorectal cancer', 2nd
International Symposium on Advances in Circulating Tumor Cells (ACTC), October
8th “11th, 2014, Crete, Greece.
European Journal of Case Reports and Clinical Images is an international open-access journal publi
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